RESOURCE: Quantifying The Mouse

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Science  20 Jan 2006:
Vol. 311, Issue 5759, pp. 311
DOI: 10.1126/science.311.5759.311b

Female mice from the C57BL/6J strain are daredevils—by rodent standards, at least. The average mouse dithers for nearly a minute before entering an open space, but C57BL/6J females scurry in after a mere 6 seconds. From brain weight to daily water intake to heat sensitivity, the Mouse Phenome project from the Jackson Laboratory in Bar Harbor, Maine, houses vital statistics on more than 100 inbred mouse strains. Mouse aficionados from around the world are stocking the site with their measurements of more than 600 anatomical, physiological, and behavioral traits. The data provide researchers with standards of comparison as they attempt to decipher the effects of different genes. Tools let users compare values among strains, tease out sex differences, and perform other analyses.

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