DATABASE: The Dope on Drugs

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Science  20 Jan 2006:
Vol. 311, Issue 5759, pp. 311
DOI: 10.1126/science.311.5759.311c

The online pharmacopoeia DrugBank profiles about 4100 approved or experimental medicines, offering data for drug designers, molecular biologists, and other researchers. Compiled by David Wishart of the University of Alberta in Edmonton, Canada, the site furnishes a DrugCard for each compound that is crammed with information in more than 80 categories. Users can corral chemical details such as solubility and molecular weight, browse nuclear magnetic resonance and mass spectra, and analyze three-dimensional structure models. For scientists investigating a drug's action, the cards include the gene and amino acid sequences of its target and identify the enzymes that break it down.

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