DATABASE: Cancer's Red Flags

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Science  27 Jan 2006:
Vol. 311, Issue 5760, pp. 445
DOI: 10.1126/science.311.5760.445e

Although cancer cells aren't foreign invaders, the immune system recognizes molecules they carry and attacks. Researchers hope that identifying these targets, or antigens, might help them devise cancer vaccines. Visitors can track down many of the antigens from abnormal cells that trigger an immune response at the Cancer Immunome Database, hosted by the international Ludwig Institute for Cancer Research. Free registration lets you peruse findings from a project that began in the 1990s and tested blood serum from cancer patients for antibodies against proteins from a variety of tumors. You can search for data on more than 1000 genes or narrow the results by tissue or cancer type. Users can also add their results to the collection.

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