News of the WeekMolecular Biology

Protein Tail Modification Opens Way for Gene Activity

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Science  10 Feb 2006:
Vol. 311, Issue 5762, pp. 757
DOI: 10.1126/science.311.5762.757a

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On page 844, a team reports that addition of a single acetyl group to a specific lysine located in the tail of so-called histone 4 can prevent chromatin folding, a prerequisite for gene expression.(Read more.)