PerspectiveCell Signaling

A Sophisticated Scaffold Wields a New Trick

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Science  10 Feb 2006:
Vol. 311, Issue 5762, pp. 789-790
DOI: 10.1126/science.1124620

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Many cellular processes are governed by proteins that are docked onto a scaffold protein. In addition to providing binding sites, scaffolds influence the signaling output of these multiprotein complexes.