SUMO Wrestles the Synapse

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Science  17 Feb 2006:
Vol. 311, Issue 5763, pp. 962-963
DOI: 10.1126/science.1124541

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The number of synapses formed in the mammalian brain is controlled by electrical activity in neurons that drives calcium inward, regulating transcription factors, including one that causes removal of synapses.

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