PerspectiveMolecular Biology

"X"-Rated Chromosomal Rendezvous

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Science  24 Feb 2006:
Vol. 311, Issue 5764, pp. 1107-1109
DOI: 10.1126/science.1124662

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Female mammals inactivate one of their two X chromosomes to ensure a dosage of genes equal to that of males who contain a single X. A brief union between the pair of X chromosomes may initiate this inactivation process.