PerspectiveBiomedicine

One Misfolded Protein Allows Others to Sneak By

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Science  10 Mar 2006:
Vol. 311, Issue 5766, pp. 1385-1386
DOI: 10.1126/science.1125246

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Summary

Proteins prone to aggregate in cells have been linked to neurodegenerative diseases. As cells try to eliminate such aggregates, other misfolded proteins may go undetected, making the cell susceptible to their toxic effects.

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