Tracing Oxygen's Imprint on Earth's Metabolic Evolution

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Science  24 Mar 2006:
Vol. 311, Issue 5768, pp. 1724-1725
DOI: 10.1126/science.1125937

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As oxygen built up in Earth's atmosphere during the Precambrian, organisms evolved more complex biochemical networks. This expansion made feasible oxygen dependent metabolisms that coopted parts of preexisting anaerobic ones.