Reducible Complexity

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Science  07 Apr 2006:
Vol. 312, Issue 5770, pp. 61-63
DOI: 10.1126/science.1126559

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How does biological complexity arise? The molecular evolution of two hormone receptors was traced from a common ancestral receptor. Through a series of mutations, receptors with distinct hormone binding properties evolved, one before the appearance of its cognate ligand.