PerspectiveDevelopmental Biology

Mixed Messages in Early Development

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Science  07 Apr 2006:
Vol. 312, Issue 5770, pp. 65-66
DOI: 10.1126/science.1126400

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MicroRNAs, molecules that repress gene expression, fine-tune early embryogenesis. Rather than expressing genetic information supplied in the egg from the mother, microRNAs direct the developing embryo to express its own genome instead.