DATABASE: Blood Work

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Science  14 Apr 2006:
Vol. 312, Issue 5771, pp. 169
DOI: 10.1126/science.312.5771.169d

Because it ferries most of the proteins in the body, blood is a rich resource for doctors trying to diagnose disease and researchers fishing for new molecules. Tap into a comprehensive list of blood proteins at the Plasma Proteome Database from Johns Hopkins University in Baltimore, Maryland, and the Institute of Bioinformatics in Bangalore, India. Stowed here are data from the literature on the more than 7500 protein variants that enter the plasma at some time. For each version, or isoform, you'll find standard genomic information such as gene and amino acid sequences. Entries also indicate the molecule's usual cellular location, whether its gene harbors any common mutations, and whether it contributes to any diseases. You can also link to PubMed abstracts of papers that furnish gene activity measurements.

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