PerspectiveNeuroscience

A Neuronal Receptor for Botulinum Toxin

See allHide authors and affiliations

Science  28 Apr 2006:
Vol. 312, Issue 5773, pp. 540-541
DOI: 10.1126/science.1127236

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution

Summary

Muscle paralysis induced by botulinum toxin A is used cosmetically to eliminate wrinkles. It preferentially enters activated neurons by binding to a synaptic vesicle protein that becomes exposed after transmitter release.