News of the WeekMolecular Biology

RNAi Safety Comes Under Scrutiny

See allHide authors and affiliations

Science  26 May 2006:
Vol. 312, Issue 5777, pp. 1121
DOI: 10.1126/science.312.5777.1121a

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


What began as an effort to craft a better hepatitis therapy using a strategy called RNA interference has ended in the deaths of dozens upon dozens of mice--a harsh safety alarm for biomedical researchers looking to RNAi as a treatment for HIV, cancer, neurodegenerative diseases, and more. (Read more.)