DATABASE: Building Blood Cells

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Science  16 Jun 2006:
Vol. 312, Issue 5780, pp. 1577b
DOI: 10.1126/science.312.5780.1577b

Determining which genes coax immature red blood cells to grow up could help researchers devise new treatments for anemia and counter the side effects of chemotherapy. To find out which genes switch on as red blood cells mature, visit the Hembase database from the National Institute of Diabetes and Digestive and Kidney Diseases. Scientists there combined their measurements of messenger RNA levels with results from previous studies on gene expression in blood cell precursors. You can track down active genes by chromosome location or by whether they take part in tasks such as defining the blood group.

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