NIH Knocks Out Key Mouse House

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Science  30 Jun 2006:
Vol. 312, Issue 5782, pp. 1863
DOI: 10.1126/science.312.5782.1863

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The Texas Institute for Genomic Medicine has knockouts for nearly a third of all mouse genes--twice what global knockout projects have achieved so far (see main text). Yet when it applied to be part of a new U.S. National Institutes of Health program to knock out as many mouse genes as possible, NIH turned it down. (Read more.)