PerspectiveMolecular Biology

Accurate RNA Siting and Splicing Gets Help from a DEK-Hand

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Science  30 Jun 2006:
Vol. 312, Issue 5782, pp. 1886-1887
DOI: 10.1126/science.1130324

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Mature messenger RNA is prepared in eukaryotes by splicing together the protein-coding sequences of precursors. A chromatin-associated protein proofreads these splice sites in the RNA, ensuring accuracy.