Report

Dodeca-CLE Peptides as Suppressors of Plant Stem Cell Differentiation

+ See all authors and affiliations

Science  11 Aug 2006:
Vol. 313, Issue 5788, pp. 842-845
DOI: 10.1126/science.1128436

You are currently viewing the abstract.

View Full Text

Abstract

In plants and animals, small peptide ligands that signal in cell-cell communication have been suggested to be a crucial component of development. A bioassay of single-cell transdifferentation demonstrates that a dodecapeptide with two hydroxyproline residues is the functional product of genes from the CLE family, which includes CLAVATA3 in Arabidopsis. The dodecapeptide suppresses xylem cell development at a concentration of 10–11 M and promotes cell division. An application, corresponding to all 26 Arabidopsis CLE protein family members, of synthetic dodecapeptides reveals two counteracting signaling pathways involved in stem cell fate.

    View Full Text

    Related Content