DATABASE: Powered by Cilia

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Science  18 Aug 2006:
Vol. 313, Issue 5789, pp. 895
DOI: 10.1126/science.313.5789.895e

Fluttering cilia speed a paramecium across a microscope slide, but the hairlike filaments are more than cellular equivalents of outboard motors. New research suggests that cilia detect fluid movement in the kidney, tune in molecular signals that help orchestrate embryonic development, and perform other stationary tasks (Science, 14 October 2005, p. 216). The new Cilia Proteome site from Johns Hopkins University in Baltimore, Maryland, is sweeping up data on all proteins found in cilia and basal bodies, the sockets that hold the filaments. You can browse the known human proteins or call up comparable molecules from model organisms such as the mouse and fruit fly.

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