PerspectiveCell Biology

Peptides, Scrambled and Stitched

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Science  08 Sep 2006:
Vol. 313, Issue 5792, pp. 1398-1399
DOI: 10.1126/science.1132882

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Cells that display peptide antigens on their surfaces for immune recognition usually cut large proteins into smaller pieces, but can also splice these to make larger, scrambled peptides.