Review

Vesicle Formation at the Plasma Membrane and Trans-Golgi Network: The Same but Different

+ See all authors and affiliations

Science  15 Sep 2006:
Vol. 313, Issue 5793, pp. 1591-1594
DOI: 10.1126/science.1118133

You are currently viewing the abstract.

View Full Text

Abstract

An elaborate vesicle transport system supports the active exchange of membranes and protein cargo between the plasma membrane and the trans-Golgi network. Many observations suggest that highly conserved mechanisms are used in vesicle formation and scission. Such similarity is found both at the level of the receptor-ligand sequestration process that uses clathrin and associated polymeric and monomeric adaptor proteins, and in the machinery used to deform and vesiculate lipid membranes.

View Full Text

Related Content