EDUCATION: Learning to Read the Dots

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Science  20 Oct 2006:
Vol. 314, Issue 5798, pp. 393
DOI: 10.1126/science.314.5798.393a

Undergraduates can get up to speed on gene chips with the Microarrays MediaBook, a snazzy animated tutorial hosted by biology professor A. Malcolm Campbell of Davidson College in North Carolina. Using the example of yeast cells growing with and without oxygen, the site leads readers through the basics of making and interpreting microarrays. Students can then dig deeper into techniques for analyzing results. They can learn about hierarchical clustering to identify genes that might work together and the significance of fold changes, the alteration in gene activity compared with controls.

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