Technical Comments

Response to Comment on Suri et al. on Diabetes Reversal in NOD Mice

Science  24 Nov 2006:
Vol. 314, Issue 5803, pp. 1243
DOI: 10.1126/science.1129917

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Abstract

Faustman et al. present no new information to explain why three independent laboratories failed to reproduce their previous results implicating spleen cell transdifferentiation in the reversal of murine type 1 diabetes. Modulation of the immunological process in nonobese diabetic (NOD) mice has been accomplished by many laboratories using different protocols and does not represent a novel finding in their work.

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