Influenza Escapes Immunity Along Neutral Networks

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Science  22 Dec 2006:
Vol. 314, Issue 5807, pp. 1884-1886
DOI: 10.1126/science.1137300

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Given that influenza virus continues to escape immunity, why is it that only one strain dominates each year? The answer may lie in neutral networks and mapping viral genotypes to antigenic phenotypes.