Molecular Biology

Remodeling with a Floral Motif

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Science  09 Feb 2007:
Vol. 315, Issue 5813, pp. 739
DOI: 10.1126/science.315.5813.739b

The transition from vegetative growth to flowering in the plant Arabidopsis is in part regulated by the gene Flowering Locus C (FLC). The expression of FLC is known to be regulated by various signaling pathways that modify the chromatin in which it is embedded. Deal et al. show that, beyond secondary modifications of existing chromatin components, the addition of a specific histone variant, H2A.Z, adds to the controls on FLC expression. Histone H2A.Z is deposited onto FLC chromatin by the Arabidopsis variant of the SWR1 complex, which has been shown in yeast to participate in the remodeling and individualizing of local chromatin domains. With histone H2A.Z as part of its chromatin packaging, the FLC gene is better poised for active expression. It is the robust expression of FLC that results in maintenance of the vegetative state. — PJH

Plant Cell 19, 10.1105/tpc.106.048447 (2007).

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