PerspectiveChemistry

Roots of Biosynthetic Diversity

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Science  06 Apr 2007:
Vol. 316, Issue 5821, pp. 60-61
DOI: 10.1126/science.1141630

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Summary

Terpenoid synthases generate an extraordinarily diverse set of natural products. Evolution of these enzymes from a common-helical ancestor has resulted in profound changes in activity.