Special Reviews

piRNAs in the Germ Line

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Science  20 Apr 2007:
Vol. 316, Issue 5823, pp. 397
DOI: 10.1126/science.1137543

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Small noncoding RNAs have emerged as potent regulators of gene expression at both transcriptional and posttranscriptional levels. Recently, a class of small RNAs that interact with Piwi proteins has been discovered in the mammalian germ line and Drosophila. These Piwi-interacting RNAs (piRNAs) represent a distinct small RNA pathway.

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