Research Article

ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage

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Science  25 May 2007:
Vol. 316, Issue 5828, pp. 1160-1166
DOI: 10.1126/science.1140321

Article Information

vol. 316 no. 5828 1160-1166

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History: 
  • Received for publication January 24, 2007
  • Accepted for publication April 6, 2007

Author Information

  1. Shuhei Matsuoka1,
  2. Bryan A. Ballif2,*,
  3. Agata Smogorzewska1,3,,
  4. E. Robert McDonald III1,,
  5. Kristen E. Hurov1,,
  6. Ji Luo1,,
  7. Corey E. Bakalarski2,
  8. Zhenming Zhao1,
  9. Nicole Solimini1,
  10. Yaniv Lerenthal4,
  11. Yosef Shiloh4,
  12. Steven P. Gygi2,,
  13. Stephen J. Elledge1,
  1. 1 Department of Genetics and Center for Genetics and Genomics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.
  2. 2 Department of Cell Biology and Taplin Biological Mass Spectrometry Facility, Harvard Medical School, Boston, MA 02115, USA.
  3. 3 Department of Pathology, Massachusetts General Hospital, Boston, MA 02214, USA.
  4. 4 Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
  1. To whom correspondence should be addressed. E-mail: selledge{at}genetics.med.harvard.edu, steven_gygi{at}hms.harvard.edu
  • * Present address: Department of Biology, University of Vermont, Burlington, VT 05405, USA.

  • These authors contributed equally to this work.

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