PerspectiveCell Signaling

Nuclear Actin as Choreographer of Cell Morphology and Transcription

Science  22 Jun 2007:
Vol. 316, Issue 5832, pp. 1710-1711
DOI: 10.1126/science.1145014

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Changes in the cell's cytoskeleton affect gene expression through a signaling circuit that involves regulation of cofactor transport and function by actin in the nucleus.