Technical Comments

Response to Comment on "Human Neuroblasts Migrate to the Olfactory Bulb via a Lateral Ventricular Extension"

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Science  19 Oct 2007:
Vol. 318, Issue 5849, pp. 393
DOI: 10.1126/science.1145164

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In contrast to a previous study of Sanai et al., our study had the advantage of using serial sagittal sections of the human basal forebrain, combined with 5-bromo-2′-deoxyuridine labeling, rigorous magnetic resonance imaging, and polymerase chain reaction analysis. We believe these methods convincingly demonstrate the presence of a rostral migratory stream in the human brain that resembles that in other mammals.

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