Figures
Fig. 2. Properties and biogenesis of piRNAs. (A) Features of Aub- and AGO3-associated piRNAs in Drosophila. Indicated are the 5′ U bias in Aub-bound piRNAs, the 10A bias in AGO3-bound piRNAs, the 5′ phosphate, and the 3′ O-methylation. (B) Ping-Pong model of piRNA biogenesis in Drosophila. Primary piRNAs are generated by an unknown mechanism and/or are maternally deposited. Those with a target are specifically amplified via a Slicer-dependent loop involving AGO3 and Aub.
Additional Files
The Piwi/piRNA Pathway Provides an Adaptive Defense in the Transposon Arms Race
Alexei A. Aravin, Gregory J. Hannon, Julius BrenneckeSupporting Online Material
This supplement contains:
Fig. S1
Table S1This file is in Adobe Acrobat PDF format.
