Research Article

GPCR Engineering Yields High-Resolution Structural Insights into β2-Adrenergic Receptor Function

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Science  23 Nov 2007:
Vol. 318, Issue 5854, pp. 1266-1273
DOI: 10.1126/science.1150609

Article Information

vol. 318 no. 5854 1266-1273

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History: 
  • Received for publication September 17, 2007
  • Accepted for publication October 11, 2007

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Author Information

  1. Daniel M. Rosenbaum1,*,
  2. Vadim Cherezov2,*,
  3. Michael A. Hanson2,
  4. Søren G. F. Rasmussen1,
  5. Foon Sun Thian1,
  6. Tong Sun Kobilka1,
  7. Hee-Jung Choi1,3,
  8. Xiao-Jie Yao1,
  9. William I. Weis1,3,
  10. Raymond C. Stevens2,,
  11. Brian K. Kobilka1,
  1. 1 Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  2. 2 Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  3. 3 Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  1. To whom correspondence should be addressed. E-mail: stevens{at}scripps.edu (R.C.S.); kobilka{at}stanford.edu (B.K.K.)
  • * These authors contributed equally to this work.

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