News of the WeekNeurobiology

Immune Molecules Prune Synapses in Developing Brain

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Science  14 Dec 2007:
Vol. 318, Issue 5857, pp. 1710-1711
DOI: 10.1126/science.318.5857.1710a

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A new study suggests that complement proteins, which tag bacteria and other bad guys for elimination, may have a surprising yet analogous function in the developing brain, tagging unwanted synapses for removal.