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An Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models

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Science  11 Apr 2008:
Vol. 320, Issue 5873, pp. 226-230
DOI: 10.1126/science.1154986

Article Information

vol. 320 no. 5873 226-230

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History: 
  • Received for publication January 8, 2008
  • Accepted for publication March 12, 2008

Author Information

  1. Lyudmila G. Burdelya1,*,
  2. Vadim I. Krivokrysenko2,*,
  3. Thomas C. Tallant3,
  4. Evguenia Strom2,
  5. Anatoly S. Gleiberman2,
  6. Damodar Gupta1,
  7. Oleg V. Kurnasov4,
  8. Farrel L. Fort2,
  9. Andrei L. Osterman4,
  10. Joseph A. DiDonato3,
  11. Elena Feinstein2,,
  12. Andrei V. Gudkov1,2,
  1. 1 Department of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
  2. 2 Cleveland BioLabs, Inc. (CBLI), Buffalo, NY14203, USA.
  3. 3 Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
  4. 4 Burnham Institute for Medical Research, La Jolla, CA 92037, USA.
  1. To whom correspondence should be addressed. E-mail: andrei.gudkov{at}roswellpark.org; efeinstein{at}cbiolabs.com
  • * These authors contributed equally to this work.

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