Technical Comments

Comment on "Genetically Determined Differences in Learning from Errors"

Science  11 Jul 2008:
Vol. 321, Issue 5886, pp. 200
DOI: 10.1126/science.1155372

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Klein et al. (Reports, 7 December 2007, p. 1642) used individuals with a polymorphism adjacent to the dopamine receptor 2 gene as naturally occurring models for reduced brain dopamine receptor density in a probabilistic learning task. We raise the concern that this polymorphism resides in the gene for the kinase ANKK1, where it causes a nonconservative amino acid exchange.

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