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Problem Solved* (*sort of)

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Science  08 Aug 2008:
Vol. 321, Issue 5890, pp. 784-786
DOI: 10.1126/science.321.5890.784

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Summary

Researchers have toiled for decades to understand how floppy chains of amino acids fold into functional proteins. Learning many of those rules has brought them to the verge of being able to make predictions about proteins they haven't even discovered.