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Science  28 Nov 2008:
Vol. 322, Issue 5906, pp. 1400
DOI: 10.1126/science.322.5906.1400a

3D Microscope Software

The 3D Measurement module of AxioVision software permits quantitative three-dimensional (3D) evaluation of microscope photos. In combination with the Inside4D module, the new software is used for the segmentation of objects in the 3D volume model, including a 3D view and the generation of a binary image. The latter can be edited using the 3D binary image editor. In addition, the module permits the user to measure interactively by clicking on individual objects in the 3D view or to automatically measure the entire image stack.

Carl Zeiss +

For information 49-(0)-3641/642770

www.zeiss.de/mikro

Metagenomic DNA

The Metagenomic DNA Isolation Kit for Water offers an alternative to traditional, time-consuming DNA isolation for metagenomic library production. The kit eliminates the need for agarose plugs, random shearing, and size-selection by pulse-field electrophoresis. The kit isolates DNA from culturable and unculturable microbes in water samples, including gram-positive bacteria. The isolated DNA can be used immediately for end repair and cloning into a suitable vector.

Epicentre Biotechnologies

For information 800-284-8474

http://www.epibio.com/

Genomic Analysis Platform

A new Small RNA Expression Analysis Kit, which runs on the Solid System high-throughput platform for DNA sequencing and genomic analysis, enables scientists to rapidly discover and profile novel small RNA molecules without prior knowledge of sequence information. The system includes a new multiplexing technology that enables the simultaneous analysis of up to 256 samples in a single sequencing run. The kit is designed to reduce the experimental variability associated with small RNA library preparation. The kit converts total RNA into a library suitable for input into the Solid System workflow for high throughput applications such as studying the function of small RNA molecules, validation of whole genome association results, targeted resequencing, chromatin immunoprecipitation, rare and somatic mutation detection, and epigenetic studies.

Applied Biosystems

For information 800-327-3002

http://www.appliedbiosystems.com/

Chiral Method Development

The Chiral Methods Development Kit for capillary electrophoresis analysis on the P/ACE MDQ System features highly sulfated cyclodextrins, a family of three chiral reagents that deliver excellent performance in the separation of most neutral, basic, and weakly acidic compounds of pharmaceutical and biological interest. Capillary electrophoresis uses significantly less sample and reagent than high-performance liquid chromatography for chiral separations, while providing broad selectivity and fast results.

Beckman Coulter

For information 714-993-8736

http://www.beckman.com/

Affinity Chromatography Resin

Strep-Tactin Superflow high capacity is an affinity chromatography resin for purification of recombinant Strep-tag proteins. The resin has improved binding capacity but the same high-protein purity as standard Strep-Tactin Superflow. The resin combines outstanding flow characteristics with superior mechanical stability. It is suitable for high flow rates and useful for purification of large protein complexes.

IBA

For information +49-551-50672-114

http://www.strep-tag.com/

Fluorescence Difference Gel Electrophoresis

The 2D Fluorescence Difference Gel Electrophoresis (DIGE) offers significant cost and time savings in comparison with traditional two-dimensional (2D) electrophoresis. Protein mixtures are labeled prior to electrophoresis with size-matched and charge-matched, spectrally resolvable CyDye fluoroflores, allowing the simultaneous separation and comparative analysis of up to three samples on a single 2D gel. Following 2D electrophoresis, the results can be scanned with the Typhoon Variable Mode Imager or the Ettan DIGE Imager. DeCyder Differential Analysis Software automatically locates and analyzes protein spots, assigning statistical confidence to every difference between the samples. The system ensures that each protein spot has its own internal standard, eliminating gel variation issues and increasing accuracy and reproducibility.

GE Healthcare

For information 732-457-8149

www.gelifesciences.com/trydige

Oxidative Stress Kit

The OxyELISA Oxidized Protein Quantitation kit provides all the reagents necessary for quantitative, high throughput detection of modified proteins in cells undergoing oxidative stress. By providing a fast and sensitive assay for oxidation, the kit can help researchers, especially neuroscientists, understand the mechanisms of cellular aging. As a result of oxidative stress, oxygen-free radicals and other reactive species introduce carbonyl groups into proteins in the cell. The OxyELISA kit detects these carbonyl groups. The kit makes use of a direct-labeled monoclonal antibody that is readily detected without a secondary antibody.

Millipore

For information 800-548-7853

http://www.millipore.com/

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Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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