PLANT SCIENCE: Two in One

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Science  30 Jan 2009:
Vol. 323, Issue 5914, pp. 562d-563d
DOI: 10.1126/science.323.5914.562d

The stress hormone abscisic acid affects a variety of processes in plants, ranging from seed germination to root tissue growth. Nevertheless, identifying specific components in the abscisic acid signal transduction pathways has not been entirely straightforward. Pandey et al. have characterized two related proteins in Arabidopsis that seem likely to function as cell surface sensors of abscisic acid. The proteins, G protein-coupled receptors (GPCRs) types 1 and 2 (GTG1 and GTG2), bind abscisic acid, are widely expressed throughout various plant tissues, and are located at the periphery of cells. Their sequences contain motifs that resemble those of GPCR transmembrane domains and of GTP-binding domains of GTPases. These proteins are highly unusual in possessing both the ligand-binding receptor function and the canonical G protein signaling capacity. — PJH

Cell 136, 136 (2009).

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