Technical Comments

Response to Comment on "Detection, Stimulation, and Inhibition of Neuronal Signals with High-Density Nanowire Transistor Arrays"

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Science  13 Mar 2009:
Vol. 323, Issue 5920, pp. 1429
DOI: 10.1126/science.1155917

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Fromherz and Voelker make incorrect assumptions about our experiments that raise serious questions about the validity of their claims. We show that our calibrated signals are consistent with previously published data and a general model with biophysically relevant parameters. Additionally, the wide variation in previously published signal amplitudes suggests caution in applying and drawing conclusions from the models of Fromherz and Voelker.

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