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Science  13 Mar 2009:
Vol. 323, Issue 5920, pp. 1507a
DOI: 10.1126/science.323.5920.1507a

Inverted Microscope with LED Light

The Leica DM IL LED is the first inverted, routine microscope to combine superior optics with state-of-the-art LED illumination. The system's low-maintenance light source with no heat build-up, long free working distance, and high stability create suitable conditions for imaging live samples. The microscope's applications include a wide variety of cell and tissue culture examinations in biology and medicine, studies in developmental biology, micromanipulation, and live-cell experiments in transgenics and electrophysiology, but the instrument's transmitted light illumination, condensers, and contrast techniques are designed for cytobiological applications. A fluorescence version is also available for applications such as green fluorescent protein labeling. Both versions can be configured with a wide range of optics and accessories.

Leica Microsystems

For information 847-405-7026

http://www.leica-microsystems.com/

Refrigerating/Heating Circulator

The Model 9712 Refrigerating/Heating Circulator features a −40°C to 200°C temperature range, ± 0.01°C temperature stability, and a 13-liter reservoir. Typical applications include the control of jacketed reactor vessels and reaction blocks as well as polymerization, polycondensation, and distillation. The variable-speed pressure/suction cup is capable of delivering pressure flow rates as high as 30 liters per minute. A sophisticated programmable controller is capable of storing up to 10 different 50-step time/temperature programs. It also allows the operator to control the temperature at the point of application, eliminating temperature shifts due to heat loss along tubing lines. Other controller features include data logging capability, multilanguage help menus, and a built-in RS-232 interface.

PolyScience

For information 800-229-7569

http://www.polyscience.com/

Bone Density Software

A new software module enables users to perform bone mineral density analysis of small animals and in vitro specimens using multienergy digital X-ray imaging when using the Kodak In-Vivo Multispectral FX, Kodak In-Vivo FX Pro, and Kodak DXS 4000 Pro systems. The software is designed for applications ranging from the study of diseases of the bone, such as arthritis and osteoporosis, to the efficacy of drugs and other treatment options that may affect bone mineral and other densities. An optional component of Kodak Molecular Imaging Software, the module makes use of a cylindrical modeling method to calculate the bone column density of selected long bones such as the tibia, fibula, metatarsals, and phalanges in small animals.

Carestream Molecular Imaging

For information 877-747-4357

http://www.carestreamhealth.com/

Genotyping Tools

The new polymerase chain reaction (PCR)-based product line Type-it is designed to make genotyping accurate and reliable, with three kits now available. The Type-it Microsatellite PCR Kit is a multiplex PCR-based kit for detection of microsatellite loci in humans, animals, plants, and bacteria using any detection platform. It allows high-yield coamplification of all fragments without the need for time-consuming optimization of PCR parameters. The Type-it Mutation Detect PCR Kit is for detection of mutations such as deletions and translocations or for preamplification of single nucleotide polymorphisms (SNPs) using multiplex PCR technology. Multiple mutation targets are amplified in parallel using one protocol. The Type-it Fast SNP Probe PCR Kit enables accurate SNP genotyping using 5'-nuclease assays. It ensures high call rates, even when targeting difficult SNP loci or when using low template amounts. Time savings of up to 40 percent are possible compared with conventional methods due to the significantly reduced PCR run times.

Qiagen

For information 240-686-7686

http://www.qiagen.com/

Cardiac Myocyte Growth Media

Clonetics Rat Cardiac Myocyte Growth Media is available for culturing rat cardiac myocytes for diverse research applications including hypertension, inflammation, ion channel flux studies, tissue engineering, and toxicology and cytotoxicology in drug development. The Myocyte Growth Media was developed and optimized for use with Clonetics Neonatal Rat Cardiac Myocytes to deliver exceptional survival and synchronized beating of these cells in culture.

Lonza Group

For information 301-898-7025

http://www.lonza.com/

Fermentation Systems

Two types of programmable fermentation systems offer a high level of performance and reproducibility. They are suitable for a wide variety of cell types, including microbes, yeast, and fungi, as well as mammalian, insect, and plant cell lines. Both models are designed for benchtop use. The CSL-FS-S modular is a small-scale fermentation system for one vessel of up to 1.5 liters. The CSL-F1 is available in four different sizes, covering capacities of 3 liters, 5 liters, 7 liters, or 10 liters, or for dual vessels. Double-jacket vessels are available for mammalian cell culture. Each system includes a built-in 15-step programmable software package and integrated control panel that enables real-time recording and communication with a personal computer. The controller can be set to keep the microbes in various growth phases for maximum yield; a pH probe enables automatic control of acid or base input via peristaltic pumps.

Cleaver Scientific

For information +44-(0)-1788-565-300

http://www.cleaverscienfic.com/

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Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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