Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

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  Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

  By Stephen G. Aller, Jodie Yu, Andrew Ward, Yue Weng, Srinivas Chittaboina, Rupeng Zhuo, Patina M. Harrell, Yenphuong T. Trinh, Qinghai Zhang, Ina L. Urbatsch, Geoffrey Chang

  Science27 Mar 2009 : 1718-1722

  A membrane protein that removes toxins and drugs from cells is caught binding two drug molecules in a large internal cavity.

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  Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

  By Stephen G. Aller, Jodie Yu, Andrew Ward, Yue Weng, Srinivas Chittaboina, Rupeng Zhuo, Patina M. Harrell, Yenphuong T. Trinh, Qinghai Zhang, Ina L. Urbatsch, Geoffrey Chang

  Science27 Mar 2009 : 1718-1722

  A membrane protein that removes toxins and drugs from cells is caught binding two drug molecules in a large internal cavity.

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