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Science  21 Aug 2009:
Vol. 325, Issue 5943, pp. 1021
DOI: 10.1126/science.325_1021a

Protein Precipitation Cartridge

The 1ml Protein Precipitation Cartridge combines the proven operational benefits of the proprietary p3 technology with the low cost and convenience of a cartridge-based separation method. Incorporating a novel, treated dual matrix frit, the new cartridge eliminates the wetting out and leaking of sample associated with many traditional protein precipitation products before the application of vacuum. The treated frit matrix also maintains high flow rates enabling quick sample preparation times.

Vascular Research Tools

EndoGRO products for vascular research include human umbilical vein endothelial cells (HUVEC) and advanced media formulations for endothelial cell culture. EndoGRO advanced media products include four uniquely optimized formulations for large vessel and microvascular endothelial cells, as well as low-passage HUVEC. These formulations have lower serum concentrations than standard endothelial cell culture media, yet have been shown to support endothelial cell growth rates that exceed other commercially available serum-containing media, while maintaining excellent cell morphology. In addition, the media have no phenol red or antimicrobials, which can cause cell stress and mask natural biological processes.

General Purpose Centrifuge

The Sorvall lines are 3-liter, general purpose centrifuges. The Sorvall ST 40 series provides ergonomic advancements for everyday sample preparations. The Sorvall Legend XT centrifuges offer high throughput processing. Both lines feature the Auto-Lock III rotor system, which enables 5-second rotor exchange without the need for tools for fast switching between applications. Operation is further simplified by the motorized lid latch and the ClickSeal bucket sealing system with its glove-friendly, one-handed open/close capability for certified biocontainment of samples. Rotor management SMARTSpin technology optimizes acceleration, braking, temperature control, and load balance for smooth runs and reproducible data. The user-friendly, backlit interface provides detailed information on operating parameters and the dedicated fast-keys enable immediate access to frequently used programs.

Chemometric Software

The WITec Project Plus software package for advanced data evaluation and chemometric image processing features various tools for multivariate analysis in the fields of confocal Raman imaging and scanning probe microscopy, such as cluster analysis and principal component analysis. Thus, hidden structures in the images can be visualized automatically, leading to quick and consistent data interpretation. In addition, a variety of advanced patent-pending analysis tools and algorithms enable comprehensive and user-friendly computerized data evaluation and image generation. The speed with which the extensive calculations behind the various algorithms and procedures can be executed provides a new level of analytical capability. WITec Project Plus can be obtained as an add-on package for the WITec Project data evaluation software.


New Polypropylene Microplates 96 and 384 feature a high level of transparency, OptiTrack high-contrast alphanumeric labeling matrix, and innovative RecoverMax well geometry for maximum sample recovery. The ultraclear wells, combined with the OptiTrack labeling, make sample and well identification faster and less error-prone than conventional polypropylene microplates. The plates are also available in high contrast white or black for improved signal-to-noise ratio for fluorescence and luminescence readings and in LoBind DNA and LoBind Protein.

Particle Size Measurement

A particle size measurement principle called induced grating (IG) allows users to measure nanoparticles with high sensitivity and reproducibility. Shimadzu's new IG-1000 particle size analyzer applies the IG method to measuring single nanoparticles. The IG-1000 offers advantages over the dynamic light scattering methods typically used. The sensitivity is the same when measuring a 1-nm particle or a 100-nm particle. Interference from clustering or contamination is significantly reduced or eliminated. The IG method eliminates interferences by using optical signals emitted by the diffraction grating formed by the particles. Even in the single nano region, users can obtain a satisfactory signal-to-noise ratio and stable measurement. The instrument's workflow involves three simple steps: inject the sample, insert the electrode, and begin analysis. It can measure particles in the 0.5 to 200 nm range in about 30 seconds.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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