The Coordinates of Truth

See allHide authors and affiliations

Science  02 Oct 2009:
Vol. 326, Issue 5949, pp. 53-54
DOI: 10.1126/science.1177637

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


The scientific method has driven conceptual inquiry for centuries and still forms the basis of scientific investigation. Yet, the hypothesis-based research paradigm itself has received scant attention recently. Here, I propose an alternative model for this paradigm, based on decision, information, and game theory. Analysis of biomedical research efforts with this model may provide a framework for predicting their likely contributions to knowledge, assessing their impact on human health, and managing research priorities.