Transcriptome Complexity in a Genome-Reduced Bacterium

Marc Güell; Vera van Noort; Eva Yus; Wei-Hua Chen; Justine Leigh-Bell; Konstantinos Michalodimitrakis; Takuji Yamada; Manimozhiyan Arumugam; Tobias Doerks; Sebastian Kühner; Michaela Rode; Mikita Suyama; Sabine Schmidt; Anne-Claude Gavin; Peer Bork; Luis Serrano

doi:10.1126/science.1176951

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Transcriptome Complexity in a Genome-Reduced Bacterium

Marc Güell¹,
Vera van Noort²,
Eva Yus¹,
Wei-Hua Chen²,
Justine Leigh-Bell¹,
Konstantinos Michalodimitrakis¹,
Takuji Yamada²,
Manimozhiyan Arumugam²,
Tobias Doerks²,
Sebastian Kühner²,
Michaela Rode²,
Mikita Suyama²,*,
Sabine Schmidt²,
Anne-Claude Gavin²,
Peer Bork²,†,
Luis Serrano¹,³,†

¹Centre for Genomic Regulation (CRG), Universitat Pompeu Fabra, Barcelona, Spain.
²European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
³Institució Catalana de Recerca i Estudis Avançats, Barcelona, Spain.

↵†To whom correspondence should be addressed. E-mail: bork{at}embl.de (P.B.); luis.serrano{at}crg.es (L.S.)

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Science 27 Nov 2009:
Vol. 326, Issue 5957, pp. 1268-1271
DOI: 10.1126/science.1176951

Marc Güell

Centre for Genomic Regulation (CRG), Universitat Pompeu Fabra, Barcelona, Spain.

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Vera van Noort

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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Eva Yus

Centre for Genomic Regulation (CRG), Universitat Pompeu Fabra, Barcelona, Spain.

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Wei-Hua Chen

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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Justine Leigh-Bell

Centre for Genomic Regulation (CRG), Universitat Pompeu Fabra, Barcelona, Spain.

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Konstantinos Michalodimitrakis

Centre for Genomic Regulation (CRG), Universitat Pompeu Fabra, Barcelona, Spain.

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Takuji Yamada

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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Manimozhiyan Arumugam

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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Tobias Doerks

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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Sebastian Kühner

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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Michaela Rode

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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Mikita Suyama

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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Sabine Schmidt

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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Anne-Claude Gavin

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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Peer Bork

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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For correspondence: bork@embl.deluis.serrano@crg.es

Luis Serrano

Centre for Genomic Regulation (CRG), Universitat Pompeu Fabra, Barcelona, Spain.Institució Catalana de Recerca i Estudis Avançats, Barcelona, Spain.

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For correspondence: bork@embl.deluis.serrano@crg.es

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