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Science  26 Feb 2010:
Vol. 327, Issue 5969, pp. 1149
DOI: 10.1126/science.327.5969.1149-a

LC Technology

The Accela 600 high performance liquid chromatography (HPLC) and Accela 1000 ultra-HPLC systems are designed to enable rapid method development and reduce solvent consumption. Both systems feature Force Feedback Control, which enables the delivery of accurate and precise gradients under all operating conditions and provides the flexibility of quaternary solvent delivery. The systems deliver excellent compositional and flow rate accuracy and precision, resulting in high levels of reproducibility, according to the manufacturer. When coupled with the Thermo Scientific LTQ Velos, these systems create a fast LC-mass spectrometry (MS) system, with increased ion trapping efficiency and lower fragmentation times. The fast scan rates of the LTQ Velos allow more MSn experiments to be carried out in shorter chromatographic runs.

Flow Cytometers

The guava easyCyte 8HT flow cytometry system is a compact, affordable, six-color detection system with 96-well automation that allows scientists to move their research out of the core lab and into their own lab. The system enables researchers to carry out highly multiplexed experiments in which six targets and eight parameters can be simultaneously analyzed in a single sample of cells. In addition to allowing researchers to analyze more targets, the six-color detection range also provides greater freedom to choose fluorescent dyes with well-separated emission spectra, which reduces the chance of overlap in the resulting signals and improves data quality.

Color Camera

The SC30 is an easy-to-use color camera for high-quality microscopy imaging that offers superior resolution and quality with accurate color reproduction. Suitable for use in both material and life science applications, this camera is designed to capture fast frame rates. Its cost-to-performance ratio makes it a suitable introductory model. With a native resolution of 2048 x 1532 pixels and multiple binning modes, the SC30 camera can achieve high levels of sensitivity and fast frame rates during live cell imaging. Using the 4x binning mode, 49 frames per second can be captured at a resolution of 508 x 384 pixels. Exposure times can be set from 57 microseconds to 1.75 seconds, enabling the user to be in complete control of the image acquisition process.

Cytometer for Large Particles

The Copast Large Particle Flow Cytometers can analyze, sort, and dispense objects that are too large (20 microns to 1,000 microns) or too delicate for traditional flow cytometers. Typical samples that can be analyzed range from small multicellular organisms (C. elegans, D. melanogaster, and zebrafish) to delicate large cells and cell clusters (adipocytes, embryoid bodies, pancreatic islets, duct cells, and hepatocytes) to seeds and beads (cells growing in or on beads and bead-based assays). Samples are analyzed one by one in a continuously flowing stream and each object is analyzed and sorted based on size, optical density, and up to three fluorescent parameters. Applications include rapid dispensing into microtiter plates for assay preparation, population enrichment prior to further experiments, isolation of rare events, and quantification of fluorescence levels of each object.

Protein A Columns

A new range of Protein A columns combines the benefits of BioVyon technology with the economy and convenience of a cartridge-based separation methodology. Designed for laboratories that handle small numbers of discrete samples, the columns offer a simple and rapid method for antibody purification, giving consistent recoveries of purified IgG. The minicolumns have a capacity of about 2.5 mg IgG, and the microcolumns have a capacity of 200 μg IgG. They can be washed and reused several times.


The Sorvall Micro-ultracentrifuge models offer versatility in rapid, small-volume processing of samples, including viruses, cellular organelles, lipoproteins, nucleic acids, and nanoparticles. Both new models offer an expanded volume range, accommodating tubes from 0.2 ml to 30 ml. These systems offer a cutting-edge drive system, providing maintenance-free performance and rotor imbalance protection for years of reliable and dependable performance. The benchtop Sorvall MTX 150 puts almost any separation within reach with a centrifugal force in excess of 1,048,000 x g. It achieves its maximum rotational speed of 150,000 rpm in just 80 seconds, and features a user-friendly LCD touch-screen interface. The Sorvall MX series offers the same versatility as the Sorvall MTX 150 in a floor model configuration. It is available in two versions, with maximum speeds of 150,000 rpm or 120,000 rpm.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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