Contents

05 March 2010
Vol 327, Issue 5970

About The Cover

Cover image expansion

COVER Scanning electron micrograph of the fruit fly Drosophila melanogaster (magnification 80 ×, eyes pseudo-colored). Sestrin, an evolutionarily conserved protein, helps protect fruit flies from age-related pathologies, including fat accumulation, muscle degeneration, and heart failure. See page 1223. Image: T. Deerinck and M. Ellisman/National Center for Microscopy and Imaging Research, University of California, San Diego