Genome-Wide Kinetics of Nucleosome Turnover Determined by Metabolic Labeling of Histones

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Science  28 May 2010:
Vol. 328, Issue 5982, pp. 1161-1164
DOI: 10.1126/science.1186777

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  • Life is Sustained by Recycled Nucleosomes

    By measuring the incorporation of newly produced histones, R. B. Deal et al. showed that nucleosomes are replaced on a fast time scale across the Drosophila genome ("Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones," Reports, 28 May 2010, p. 1161). This important finding indicates that if epigenetic memory is carried by chemical modifications of nucleosomes, then this m...

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    Competing Interests: None declared.