Is the Tide Turning for New Malaria Medicines?

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Science  03 Sep 2010:
Vol. 329, Issue 5996, pp. 1153-1154
DOI: 10.1126/science.1194923

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Every so often, the tide turns in a field of science. In malaria research, for a while an approach called “rational design” held sway, with great optimism that new drugs would emerge from understanding the biology of the malaria parasite at the molecular level. On page 1175 of this issue, however, Rottmann et al. (1) take our thinking back up to the level of the parasite.