Technical Comments

Comment on “The Human K-Complex Represents an Isolated Cortical Down-State”

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Science  01 Oct 2010:
Vol. 330, Issue 6000, pp. 35
DOI: 10.1126/science.1182138

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Cash et al. (Reports, 22 May 2009, p. 1084) argue that the human K-complex, a defining characteristic of slow-wave sleep, is a unipolar electroencephalogram (EEG) wave reflecting a simple neuronal hyperpolarizing event. We disagree with this conclusion and point to several confounding aspects of the study.

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