News FocusBREAKTHROUGH OF THE YEAR

The Runners-Up

Science  17 Dec 2010:
Vol. 330, Issue 6011, pp. 1605-1607
DOI: 10.1126/science.330.6011.1605

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Summary

A synthetic genome inserted into a bacterium in place of the organism's original DNA and the two-thirds-complete Neandertal genome sequence topped the list of this year's runners-up for Breakthrough of the Year. Other notable discoveries included next-generation genomics, souped-up cellular reprogramming, exome sequencing, quantum simulators, molecular dynamics simulations, knockout rats, and HIV prophylaxis.